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science

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publications

— our mission

Cells offer numerous examples of complex systems that perform specific tasks with remarkable precision and efficiency.
We aim to re-engineer these natural systems using the technique of DNA origami.​

— meeting report

Elucidating the nanoscopic organization and dynamics of the nuclear pore complex

Kevin N. Baumann, Eva Bertosin, Anders Barth, Cees Dekker, Roderick Y.H. Lim
Nucleus 2025
https://doi.org/10.1080/19491034.2025.2510106

— perspective

A roadmap toward the synthesis of life

Christine M.E. Kriebisch, Olga Bantysh, Lorena Baranda Pellejero, Andrea Belluati, Eva Bertosin et al.
Chem 2025
https://doi.org/10.1016/j.chempr.2024.102399

— research article

Compliant DNA Origami Nanoactuators as Size‐Selective Nanopores

Ze Yu, Anna V. Baptist, Susanne C. M. Reinhardt, Eva Bertosin, Cees Dekker, Ralf Jungmann, Amelie Heuer-Jungemann, Sabina Caneva
Advanced Materials 2024
https://doi.org/10.1002/adma.202405104

— research article

Orientation-Locked DNA Origami for Stable Trapping of Small Proteins in the Nanopore Electro-Osmotic Trap

Chenyu Wen, Eva Bertosin, Xin Shi, Cees Dekker, Sonja Schmid
Nano Letters 2023
https://pubs.acs.org/doi/10.1021/acs.nanolett.2c03569

— research article

A DNA origami rotary ratchet motor

Anna-Katharina Pumm, Wouter Engelen, Enzo Kopperger, Jonas Isensee, Matthias Vogt, Viktorija Kozina, Massimo Kube, Maximilian N. Honemann, Eva Bertosin, Martin Langecker, Ramin Golestanian, Friedrich C. Simmel, Hendrik Dietz
Nature 2022
https://doi.org/10.1038/s41586-022-04910-y

— research article

Cryo-Electron Microscopy and Mass Analysis of Oligolysine-Coated DNA Nanostructures

Eva Bertosin, Pierre Stömmer, Elija Feigl, Maximilian Wenig, Maximilian N. Honemann, and Hendrik Dietz
ACS Nano 2021
https://dx.doi.org/10.1021/acsnano.0c10137

— research article

A nanoscale reciprocating rotary mechanism with coordinated mobility control

Eva Bertosin, Christopher M. Maffeo, Thomas Drexler, Maximilian N. Honemann, Aleksei Aksimentiev, Hendrik Dietz
Nature Communications 2021
https://doi.org/10.1038/s41467-021-27230-7

— research article

Tailored Peptide Phenyl Esters Block ClpXP Proteolysis by an Unusual Breakdown into a Heptamer–Hexamer Assembly

Markus Lakemeyer, Eva Bertosin, Friederike Möller, Dóra Balogh, Ralf Strasser, Hendrik Dietz, Stephan A. Sieber
Angewandte Chemie International Edition 2019
https://doi.org/10.1002/anie.201901056

— research article

DNA origami scaffold for studying intrinsically disordered proteins of the nuclear pore complex

Philip Ketterer, Adithya N. Ananth, Diederik S. Laman Trip, Ankur Mishra, Eva Bertosin, Mahipal Ganji, Jaco van der Torre, Patrick Onck, Hendrik Dietz, Cees Dekker
Nature Communications 2018
https://doi.org/10.1038/s41467-018-03313-w

— research article

Structure and mechanism of the two-component α-helical pore-forming toxin YaxAB

Bastian Bräuning, Eva Bertosin, Florian Praetorius, Christian Ihling, Alexandra Schatt, Agnes Adler, Klaus Richter, Andrea Sinz, Hendrik Dietz, Michael Groll
Nature Communications 2018
https://doi.org/10.1038/s41467-018-04139-2

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