Affiliations and Support
— research
Cells offer numerous examples of complex systems that perform specific tasks with remarkable precision and efficiency.
We aim to re-engineer these natural systems using the technique of DNA origami.
Our aim is to construct functional DNA origami nanostructures inspired by natural protein complexes.
Our aim is to use DNA origami to manipulate cellular membranes in vivo.
— inside our toolbox
These are the core techniques driving our research:
— DNA origami
— Single-molecule biophysics
— Transmission electron microscopy
— Fluorescence microscopy
— Cryo-electron microscopy
— Flow-induced dispersion analysis
Elucidating the nanoscopic organization and dynamics of the NPC_
Baumann et al., Nucleus 2025
We report key recent advancements discussed at the Selective Transport Control in Biological and Biomimetic Nanopores meeting (Monte Verità, Switzerland, 2024) that gathered nuclear pore complex (NPC) experts from a range of disciplines.
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A roadmap towards the synthesis of Life_
Kriebisch et al., Chem 2024
What are the challenges that we are currently facing to build life from non-life? In this perspective, we present a roadmap toward the engineering of life based on discussions during a two-week workshop with scientists from all around the world.
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The Team_
Latest news_